Lechat B, Hirotsu C, Appleton S, Younes M, Adams RJ, Vakulin A, Hansen K, Zajamsek B, Wittert G, Catcheside P, Heinzer R, Eckert DJ. A novel EEG marker predicts perceived SLEEPINESS AND poor sleep quality. Sleep. 2022 Mar 4:zsac051. doi: 10.1093/sleep/zsac051.

Contact: Robert Adams

This study aims to determine if a novel EEG-derived continuous index of sleep depth/alertness, the odds ratio product (ORP), predicts self-reported daytime sleepiness and poor sleep quality in two large population-based cohorts.

It was found that ORP, measured during wake periods, predicts poor sleep quality in two independent cohorts. Consistent with insomnia symptomatology of poor perceived sleep in the absence of excessive daytime sleepiness, ORPwake may provide valuable objective mechanistic insight into physiological hyperarousal.