6PGD

The role of the 6PGD protein in prostate cancer hormone treatment resistance

The role of the 6PGD protein in prostate cancer hormone treatment resistance

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth.
Gillis JL, Hinneh JA, Ryan NK, Irani S, Moldovan M, Quek LE, Shrestha RK, Hanson AR, Xie J, Hoy AJ, Holst J, Centenera MM, Mills IG, Lynn DJ, Selth LA, Butler LM. Elife. 2021 Aug 12;10:e62592. doi: 10.7554/eLife.62592. PMID: 34382934.
Contact: Luke Selth