cancer progression

Culturing pancreatic tumour tissue provides novel ways to improve cancer knowledge

Culturing pancreatic tumour tissue provides novel ways to improve cancer knowledge

Ex vivo culture of intact human patient derived pancreatic tumour tissue.
Kokkinos J, Sharbeen G, Haghighi KS, Ignacio RMC, Kopecky C, Gonzales-Aloy E, Youkhana J, Timpson P, Pereira BA, Ritchie S, Pandzic E, Boyer C, Davis TP, Butler LM, Goldstein D, McCarroll JA, Phillips PA. Sci Rep. 2021 Jan 21;11(1):1944. doi: 10.1038/s41598-021-81299-0.
Contact: Lisa Butler

Androgen receptor (AR) signalling and drug resistance in prostate cancer

Androgen receptor (AR) signalling and drug resistance in prostate cancer

The androgen receptor (AR) is a key protein in prostate cells that binds androgen sex hormones (e.g. testosterone) that drive prostate cancer development and progression. We are leading research developing and trialling new androgen receptor targeted drugs to combat drug resistance and fatal disease.

The University of Adelaide
Contact:
Professor Lisa Butler, Associate Professor Luke Selth