Lipids (fatty acids) can profoundly influence prostate cancer cell behaviour, including disease aggressiveness and resistance to drugs. We are using this knowledge to i) develop sensitive probes for lipid biomarkers to predict disease behaviour and the likely response of men to different prostate cancer drugs to better guide treatment and improve health outcomes, ii) evaluate lipid enzyme inhibitors as a novel drug approach for treating prostate cancer, and iii) better inform lifestyle-related prevention strategies to reduce the risk of aggressive disease.

Prostate Cancer Research Group
South Australian Health and Medical Research Institute (SAHMRI), The University of Adelaide
Contact: Professor Lisa Butler