Congratulations to the Centre’s 2022 Honours students on their scholarship awards and we wish them all the best for their research and training
Validation of the Male Depression Risk Scale short form in a cross-sectional study of Australian men. Herreen D, Rice S, Zajac I. Brief assessment of male depression in clinical care:BMJ Open. 2022 Mar 28;12(3):e053650. doi: 10.1136/bmjopen-2021-053650.
Contact: Dr Ian Zajac
To celebrate International Women’s Day, the Centre is highlighting some of the fantastic women of men’s health that have been supported by the Centre and are achieving great work in the field. FCMHW encourages and commends the involvement of women in men’s health and hopes to further support it in the future.
Aberrations in circulating ceramide levels are associated with poor clinical outcomes across localised and metastatic prostate cancer. Lin HM, Huynh K, Kohli M, Tan W, Azad AA, Yeung N, Mahon KL, Mak B, Sutherland PD, Shepherd A, Mellett N, Docanto M, Giles C, Centenera MM, Butler LM, Meikle PJ, Horvath LG.
Prostate Cancer Prostatic Dis. 2021 Mar 21. doi: 10.1038/s41391-021-00338-z.
Contact: Lisa Butler
In a prospective clinical trial across 5 Australian sites, we are giving men with prostate cancer statins (cholesterol lowering drug) to examine whether they reverse a poor prognosis lipidome signature.
ANZ Clinical Trials Register Study ID: ACTRN12617000965303 (NSW Study)
Contact: Professor Lisa Butler
Lipids (fatty acids) can profoundly influence prostate cancer cell behaviour, including disease aggressiveness and resistance to drugs. We are using this knowledge to i) develop sensitive probes for lipid biomarkers to predict disease behaviour and the likely response of men to different prostate cancer drugs to better guide treatment and improve health outcomes, ii) evaluate lipid enzyme inhibitors as a novel drug approach for treating prostate cancer, and iii) better inform lifestyle-related prevention strategies to reduce the risk of aggressive disease.
Prostate Cancer Research Group
South Australian Health and Medical Research Institute (SAHMRI), The University of Adelaide
Contact: Professor Lisa Butler
