Effects of androgens on glucose metabolism. Umapathysivam M, Grossmann M, Wittert GA. Best Pract Res Clin Endocrinol Metab. 2022 Mar 31:101654. doi: 10.1016/j.beem.2022.101654.
Contact: Gary Wittert
Validation of the Male Depression Risk Scale short form in a cross-sectional study of Australian men. Herreen D, Rice S, Zajac I. Brief assessment of male depression in clinical care:BMJ Open. 2022 Mar 28;12(3):e053650. doi: 10.1136/bmjopen-2021-053650.
Contact: Dr Ian Zajac
To celebrate International Women’s Day, the Centre is highlighting some of the fantastic women of men’s health that have been supported by the Centre and are achieving great work in the field. FCMHW encourages and commends the involvement of women in men’s health and hopes to further support it in the future.
Effects of androgens on glucose metabolism. Umapathysivam M, Grossmann M, Wittert GA. Best Pract Res Clin Endocrinol Metab. 2022 Mar 31:101654. doi: 10.1016/j.beem.2022.101654.
Contact: Gary Wittert
Testosterone, Diabetes Risk, and Diabetes Prevention in Men. Yeap BB, Wittert GA. Endocrinol Metab Clin North Am. 2022 Mar;51(1):157-172. doi: 10.1016/j.ecl.2021.11.004. Epub 2022 Feb 8. PMID: 35216714.
Contact: Gary Wittert
Recovery of Male Reproductive Function After Ceasing Prolonged Testosterone Undecanoate Injections
Handelsman DJ, Desai R, Conway AJ, Shankara-Narayana N, Stuckey BG, Inder WJ, Grossmann M, Yeap BB, Jesudason D, Ly LP, Bracken K, Wittert GA. Eur J Endocrinol. 2022 Jan 1:EJE-21-0608.R2. doi: 10.1530/EJE-21-0608. Online ahead of print.PMID: 35000898
Contact: Gary Wittert
Lower serum testosterone concentrations are associated with a higher incidence of dementia in men: The UK Biobank prospective cohort study.
Marriott RJ, Murray K, Flicker L, Hankey GJ, Matsumoto AM, Dwivedi G, Antonio L, Almeida OP, Bhasin S, Dobs AS, Handelsman DJ, Haring R, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Yeap BB. Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12529. Online ahead of print.PMID: 34978125
Contact: Gary Wittert
Associations of Serum Testosterone and Sex Hormone-Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men.
Yeap BB, Marriott RJ, Antonio L, Raj S, Dwivedi G, Reid CM, Anawalt BD, Bhasin S, Dobs AS, Handelsman DJ, Hankey GJ, Haring R, Matsumoto AM, Norman PE, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Ann Intern Med. 2021 Dec 28. doi: 10.7326/M21-0551. Online ahead of print.PMID: 34958606
Contact: Gary WIttert
Associations of serum testosterone and sex hormone-binding globulin with incident cardiovascular events in middle-aged to older men.
Yeap BB, Marriott RJ, Antonio L, Raj S, Dwivedi G, Reid CM, Anawalt BD, Bhasin S, Dobs AS, Handelsman DJ, Hankey GJ, Haring R, Matsumoto AM, Norman PE, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Ann Intern Med. 2021 Dec 28. doi: 10.7326/M21-0551. Epub ahead of print. PMID: 34958606.
Contact: Gary.Wittert
Dysregulation of the Hypothalamic-Pituitary-Testicular Axis due to Energy Deficit.
Grossmann M, Wittert GA.J Clin Endocrinol Metab. 2021 Jul 15:dgab517. doi: 10.1210/clinem/dgab517. Online ahead of print.PMID: 34264314
Contact: Gary Wittert
Effect of Testosterone treatment on bone microarchitecture and bone mineral density in men: a two-year RCT.Ng Tang Fui M, Hoermann R, Bracken K, Handelsman DJ, Inder WJ, Stuckey BGA, Yeap BB, Ghasem-Zadeh A, McLachlan R, Robledo KP, Jesudason D, Zajac JD, Wittert GA, Grossmann M.
.J Clin Endocrinol Metab. 2021 Mar 8:dgab149. doi: 10.1210/clinem/dgab149.
Contact: Gary Wittert
Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year, phase 3b trial.
Wittert G, Bracken K, Robledo KP, Grossmann M, Yeap BB, Handelsman DJ, Stuckey B, Conway A, Inder W, McLachlan R, Allan C, Jesudason D, Fui MNT, Hague W, Jenkins A, Daniel M, Gebski V, Keech A. Lancet Diabetes Endocrinol. 2021 Jan;9(1):32-45. doi: 10.1016/S2213-8587(20)30367-3.
Contact: Gary Wittert
Serum testosterone is inversely, and sex hormone-binding globulin directly, associated with all-cause mortality in men
Yeap BB, Marriott RJ, Antonio L, Chan YX, Raj S, Dwivedi G, Reid CM, Anawalt BD, Bhasin S, Dobs AS, Hankey GJ, Matsumoto AM, Norman PE, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Murray K. J Clin Endocrinol Metab. 2020 Oct 16:dgaa743. doi: 10.1210/clinem/dgaa743.
Contact: Bu Yeap
New research by the Freemasons Centre for Male Health and Wellbeing has shown the public perception that ‘too much testosterone’ increases stereotypical masculine traits in men might not be true at all.
The Australian-first study analysed testosterone levels of more than 500 men aged 35 and older and assessed their self-perceptions of masculinity through a questionnaire that rated six different indicators of masculinity.
Research leader and endocrinologist, Professor Gary Wittert, said the results showed no relationship between testosterone and masculinity.
“Masculinity traditionally tends to be characterised by traits such as toughness, emotional control, physical strength, competitiveness and sexual competency,” Professor Wittert said.
“The six areas of self-perceived masculinity evaluated in this study were physical strength, optimism, sexuality, self-reliability, family responsibility and ability to take action. We found there was no link between the participants’ self-perceptions of these traits and their testosterone concentration.”
Professor Wittert said the study clearly showed that psychosocial factors and physical disorders are the variants underpinning self-perceived masculinity.
“The key factors negatively impacting scores included a history of anxiety, being without a partner and most significantly living with moderate to severe erectile dysfunction,” he said.
Men with bigger waistlines and varying levels of erectile dysfunction were less confident sexually and less optimistic, while males with partners viewed themselves as physically stronger and more responsible than those who had been widowed or divorced.
“The notion that typical traits of masculinity are linked to testosterone and are risk factors for poor health no longer stand up to scrutiny,” Prof Wittert said.
“Accumulating evidence suggests that aspects of typical masculinity might be associated with better health and health outcomes for men,” Prof Wittert said.
Enquiries to: Professor Gary Wittert
Sociodemographic, lifestyle and medical influences on serum testosterone and sex hormone-binding globulin in men from UK Biobank
Yeap BB, Marriott RJ, Antonio L, Bhasin S, Dobs AS, Dwivedi G, Flicker L, Matsumoto AM, Ohlsson C, Orwoll ES, Raj S, Reid CM, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Clin Endocrinol (Oxf). 2020 Sep 26. doi: 10.1111/cen.14342.
Contact: Bu Yeap
The University of Adelaide and South Australian Health and Medical Research Institute (SAHMRI)
Contact: Professor Gary Wittert