An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.
Davies A, Nouruzi S, Ganguli D, Namekawa T, Thaper D, Linder S, Karaoğlanoğlu F, Omur ME, Kim S, Kobelev M, Kumar S, Sivak O, Bostock C, Bishop J, Hoogstraat M, Talal A, Stelloo S, van der Poel H, Bergman AM, Ahmed M, Fazli L, Huang H, Tilley W, Goodrich D, Feng FY, Gleave M, He HH, Hach F, Zwart W, Beltran H, Selth L, Zoubeidi A.
Nat Cell Biol. 2021 Sep;23(9):1023-1034. doi: 10.1038/s41556-021-00743-5. Epub 2021 Sep 6.PMID: 34489572
Contact: Luke Selth

Early chemotherapy for testicular cancer does extend time to relapse- UK study

Early chemotherapy for testicular cancer does extend time to relapse- UK study

Features and management of late relapse of nonseminomatous germ cell tumour. Jay APM, Aldiwani M, O'Callaghan ME, Pearce AK, Huddart RA, Mayer E, Reid AH, Nicol DL. Eur Urol Open Sci. 2021 Jun 7;29:82-88. doi: 10.1016/j.euros.2021.04.008. PMID: 34337537;
Contact: Michael O’Callaghan



PIEZO-ICSI increases fertilization rates compared with standard ICSI

PIEZO-ICSI increases fertilization rates compared with standard ICSI

PIEZO-ICSI increases fertilization rates compared with standard ICSI: a prospective cohort study. Zander-Fox D, Lam K, Pacella-Ince L, Tully C, Hamilton H, Hiraoka K, McPherson NO, Tremellen K. Reprod Biomed Online. 2021 May 31:S1472-6483(21)00279-0. doi: 10.1016/j.rbmo.2021.05.020. Epub ahead of print. PMID: 34326006.
Contact: Dr Nicole McPherson


World first study to catalog all lipid species in prostate cancer - informing future treatment strategies

World first study to catalog all lipid species in prostate cancer - informing future treatment strategies

Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition.
Butler LM, Mah CY, Machiels J, Vincent AD, Irani S, Mutuku SM, Spotbeen X, Bagadi M, Waltregny D, Moldovan M, Dehairs J, Vanderhoydonc F, Bloch K, Das R, Stahl J, Kench JG, Gevaert T, Derua R, Waelkens E, Nassar ZD, Selth LA, Trim PJ, Snel MF, Lynn DJ, Tilley WD, Horvath LG, Centenera MM, Swinnen JV.
Cancer Res. 2021 Aug 6:canres.3863.2020. doi: 10.1158/0008-5472.CAN-20-3863. PMID: 34362796
Contact: Lisa Butler

Optimisation of on-line exercise guide for men with metastatic prostate cancer

Optimisation of on-line exercise guide for men with metastatic prostate cancer

Usability, acceptability, and safety analysis of a computer-tailored web-based exercise intervention (ExerciseGuide) for individuals with metastatic prostate cancer: Multi-methods laboratory-based study..
Evans HE, Forbes CC, Galvão DA, Vandelanotte C, Newton RU, Wittert G, Chambers S, Vincent AD, Kichenadasse G, Girard D, Brook N, Short CE. JMIR Cancer. 2021 Jul 28;7(3):e28370. doi: 10.2196/28370. PMID: 34318759;
Contact: Holly Evans

Clinical review of inadequate nutrition and excessive energy expenditure on testosterone in men

Clinical review of inadequate nutrition and excessive energy expenditure on testosterone in men

Dysregulation of the Hypothalamic-Pituitary-Testicular Axis due to Energy Deficit.
Grossmann M, Wittert GA.J Clin Endocrinol Metab. 2021 Jul 15:dgab517. doi: 10.1210/clinem/dgab517. Online ahead of print.PMID: 34264314
Contact: Gary Wittert

Extending the Male Depression Risk Scale for use with older men

Extending the Male Depression Risk Scale for use with older men

High fat diet in males impairs female immune adaptation for pregnancy in mice

High fat diet in males impairs female immune adaptation for pregnancy in mice

High fat diet alters male seminal plasma composition to impair female immune adaptation for pregnancy in mice. Schjenken JE, Moldenhauer LM, Sharkey DJ, Chan HY, Chin PY, Fullston T, McPherson NO, Robertson SA.Endocrinology. 2021 Jun 25:bqab123. doi: 10.1210/endocr/bqab123. PMID: 34170298
Contact: Nicole McPherson