An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.
Davies A, Nouruzi S, Ganguli D, Namekawa T, Thaper D, Linder S, Karaoğlanoğlu F, Omur ME, Kim S, Kobelev M, Kumar S, Sivak O, Bostock C, Bishop J, Hoogstraat M, Talal A, Stelloo S, van der Poel H, Bergman AM, Ahmed M, Fazli L, Huang H, Tilley W, Goodrich D, Feng FY, Gleave M, He HH, Hach F, Zwart W, Beltran H, Selth L, Zoubeidi A.
Nat Cell Biol. 2021 Sep;23(9):1023-1034. doi: 10.1038/s41556-021-00743-5. Epub 2021 Sep 6.PMID: 34489572
Contact: Luke Selth
Australian Research Council Grant on environmental impacts on sperm and offspring health
Obesity, fatty acids and prostate cancer therapy resistance
Tumour fatty acid metabolism in the context of therapy resistance and obesity.
Hoy AJ, Nagarajan SR, Butler LM. Nat Rev Cancer. 2021 Aug 20. doi: 10.1038/s41568-021-00388-4. PMID: 34417571
Contact: Lisa Butler
Antioxidant idebenone for sperm of older men may be beneficial in improving embryo quality
Improving sperm oxidative stress and embryo quality in advanced paternal age using Idebenone in vitro-A proof-of-concept study. Nikitaras V, Zander-Fox D, McPherson NO. Antioxidants (Basel). 2021 Jul 5;10(7):1079. doi: 10.3390/antiox10071079. PMID: 34356315;
Contact: Nicole McPherson
Early chemotherapy for testicular cancer does extend time to relapse- UK study
Features and management of late relapse of nonseminomatous germ cell tumour. Jay APM, Aldiwani M, O'Callaghan ME, Pearce AK, Huddart RA, Mayer E, Reid AH, Nicol DL. Eur Urol Open Sci. 2021 Jun 7;29:82-88. doi: 10.1016/j.euros.2021.04.008. PMID: 34337537;
Contact: Michael O’Callaghan
PIEZO-ICSI increases fertilization rates compared with standard ICSI
PIEZO-ICSI increases fertilization rates compared with standard ICSI: a prospective cohort study. Zander-Fox D, Lam K, Pacella-Ince L, Tully C, Hamilton H, Hiraoka K, McPherson NO, Tremellen K. Reprod Biomed Online. 2021 May 31:S1472-6483(21)00279-0. doi: 10.1016/j.rbmo.2021.05.020. Epub ahead of print. PMID: 34326006.
Contact: Dr Nicole McPherson
World first study to catalog all lipid species in prostate cancer - informing future treatment strategies
Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition.
Butler LM, Mah CY, Machiels J, Vincent AD, Irani S, Mutuku SM, Spotbeen X, Bagadi M, Waltregny D, Moldovan M, Dehairs J, Vanderhoydonc F, Bloch K, Das R, Stahl J, Kench JG, Gevaert T, Derua R, Waelkens E, Nassar ZD, Selth LA, Trim PJ, Snel MF, Lynn DJ, Tilley WD, Horvath LG, Centenera MM, Swinnen JV.
Cancer Res. 2021 Aug 6:canres.3863.2020. doi: 10.1158/0008-5472.CAN-20-3863. PMID: 34362796
Contact: Lisa Butler
Optimisation of on-line exercise guide for men with metastatic prostate cancer
Usability, acceptability, and safety analysis of a computer-tailored web-based exercise intervention (ExerciseGuide) for individuals with metastatic prostate cancer: Multi-methods laboratory-based study..
Evans HE, Forbes CC, Galvão DA, Vandelanotte C, Newton RU, Wittert G, Chambers S, Vincent AD, Kichenadasse G, Girard D, Brook N, Short CE. JMIR Cancer. 2021 Jul 28;7(3):e28370. doi: 10.2196/28370. PMID: 34318759;
Contact: Holly Evans
Clinical review of inadequate nutrition and excessive energy expenditure on testosterone in men
Dysregulation of the Hypothalamic-Pituitary-Testicular Axis due to Energy Deficit.
Grossmann M, Wittert GA.J Clin Endocrinol Metab. 2021 Jul 15:dgab517. doi: 10.1210/clinem/dgab517. Online ahead of print.PMID: 34264314
Contact: Gary Wittert
Extending the Male Depression Risk Scale for use with older men
Extending the Male Depression Risk Scale for use with older men: the effect of age on factor structure and associations with psychological distress and history of depression.
Herreen D, Rice S, Ward L, Zajac I. Aging & Mental Health 2021. DOI: 10.1080/13607863.2021.1947966
Contact: Danielle Herreen
Welcome Jacob Brain: Uni of Nottingham/Uni of Adelaide Joint PhD Program student
High fat diet in males impairs female immune adaptation for pregnancy in mice
High fat diet alters male seminal plasma composition to impair female immune adaptation for pregnancy in mice. Schjenken JE, Moldenhauer LM, Sharkey DJ, Chan HY, Chin PY, Fullston T, McPherson NO, Robertson SA.Endocrinology. 2021 Jun 25:bqab123. doi: 10.1210/endocr/bqab123. PMID: 34170298
Contact: Nicole McPherson
Strengthening Men’s Health Promotion in Australia
Strengthening men’s health promotion in Australia: Poole, G., Smith, J. & Gupta, G. Health Promotion Journal of Australia..
Contact: James Smith
MRFF grant to FCMHW NT & SA for Aboriginal and Torres Strait Islander men's heath services
Improving sperm oxidative stress and embryo quality in advanced paternal age using idebenone in vitro
Improving sperm oxidative stress and embryo quality in advanced paternal age using idebenone in vitro—A proof-of-concept study
V Nikitaras, D Zander-Fox, NO McPherson - Antioxidants, 2021
Contact: Nicole McPherson