Generating new knowledge informing further research, policy and practice

FCMHW members lead and collaborate on biomedical, public health, clinical and social research programs that have, to date, generated new knowledge and understandings which have been cited more than 22,000 times; providing evidence to guide and inform policy agendas, drug development pipelines for prostate cancer, preventative health strategies (cancer screening, lifestyle interventions), education resources and programs, diagnostics development, clinical guidelines, and health service improvements including delivery, support care and on-line services.

Visit Google Scholar  for the full listing of the Centre's research publications.

 
 

Latest Publications

Featured
Improved tumor cell invasiveness measurement using digital holographic microscopy

Optical Cellular Micromotion: A new paradigm to measure tumor cells Invasion within gels mimicking the 3D tumor environments.
Guo Z, Yang CT, Chien CC, Selth LA, Bagnaninchi PO, Thierry B. Small Methods. 2022 Jun 28:e2200471. doi: 10.1002/smtd.202200471.
Contact: Luke Selth

The effect of testosterone in the prevention of type-2 diabetes

Effects of androgens on glucose metabolism. Umapathysivam M, Grossmann M, Wittert GA. Best Pract Res Clin Endocrinol Metab. 2022 Mar 31:101654. doi: 10.1016/j.beem.2022.101654.

Contact: Gary Wittert

Level playing field: young males, masculinity and mental wellbeing through sport

Level playing field: young males, masculinity and mental wellbeing through sport.
Drummond, M., Wadham, B., Prichard, I. et al. BMC Public Health 22, 756 (2022). https://doi.org/10.1186/s12889-022-13200-1.
Contact: Murray Drummond

Validation of a short form Male Depression Risk Scale

Validation of the Male Depression Risk Scale short form in a cross-sectional study of Australian men. Herreen D, Rice S, Zajac I. Brief assessment of male depression in clinical care:BMJ Open. 2022 Mar 28;12(3):e053650. doi: 10.1136/bmjopen-2021-053650.

Contact: Dr Ian Zajac

Reviewing spatial approaches to target identification and treatment decision-making for prostate cancer.

Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics. Cancers. Mutuku SM, Spotbeen X, Trim PJ, Snel MF, Butler LM, Swinnen JV. (Basel). 2022 Mar 27;14(7):1702. doi: 10.3390/cancers14071702.

Contact: Lisa Butler

Using Patient-Derived Explants in Prostate Cancer Research

Harnessing the Heterogeneity of Prostate Cancer for Target Discovery Using Patient-Derived Explants. Centenera MM, Vincent AD, Moldovan M, Lin HM, Lynn DJ, Horvath LG, Butler LM. Cancers (Basel). 2022 Mar 28;14(7):1708. doi: 10.3390/cancers14071708.

Contact: Lisa Butler

Adherence to secondary prevention for patients with cardiovascular disease and mental health disorders

Understandings and experiences of adherence to secondary prevention for patients with cardiovascular disease and comorbid depression or anxiety. Cosh SM, Pinto R, Denson L, Tully PJ Psychol Health Med. 2022 Mar 31:1-8. doi: 10.1080/13548506.2022.2060515. Epub ahead of print. PMID: 35356823.
Contact: Phillip Tully

Geneotypes of men with advanced prostate cancer who may benefit from metabolic therapies

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer. Mak B, Lin HM, Kwan EM, Fettke H, Tran B, Davis ID, Mahon K, Stockler MR, Briscoe K, Marx G, Zhang A, Crumbaker M, Tan W, Huynh K, Meikle TG, Mellett NA, Hoy AJ, Du P, Yu J, Jia S, Joshua AM, Waugh DJ, Butler LM, Kohli M, Meikle PJ, Azad AA, Horvath LG. BMC Med. 2022 Mar 25;20(1):112. doi: 10.1186/s12916-022-02298-0.
Contact: Lisa Butler

Identifying the most appropriate bone scan strategy for Australian men with prostate cancer

Evaluation of selective bone scan staging in prostate cancer - external validation of current strategies and decision-curve analysis.

Hiwase MD, Jay A, Bulamu N, Teh J, Paterson F, Kichenadasse G, Vincent AD, O'Callaghan M; South Australian Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC). Prostate Cancer Prostatic Dis. 2022 Mar 14. doi: 10.1038/s41391-022-00515-8.


Contact: Andrew Vincent

Long term toxicity following radiotherapy for prostate cancer - A review

Long term genitourinary toxicity following curative intent intensity-modulated radiotherapy for prostate cancer: a systematic review and meta-analysis.

David R, Buckby A, Kahokehr AA, Lee J, Watson DI, Leung J, O'Callaghan ME. Prostate Cancer Prostatic Dis. 2022 Mar 8. doi: 10.1038/s41391-022-00520-x.
Contact: Michael O’Callaghan

"She'll Be Right, Mate": A Mixed Methods Analysis of Skin Cancer Prevention Practices among Australian Farmers-An At-Risk Group

"She'll Be Right, Mate": A Mixed Methods Analysis of Skin Cancer Prevention Practices among Australian Farmers-An At-Risk Group. Trenerry C, Fletcher C, Wilson C, Gunn K. Int J Environ Res Public Health. 2022 Mar 3;19(5):2940. doi: 10.3390/ijerph19052940.


Contact: Kate Gunn

EEG marker predicts perceived sleepiness and poor sleep quality

A novel EEG marker predicts perceived SLEEPINESS AND poor sleep quality. Lechat B, Hirotsu C, Appleton S, Younes M, Adams RJ, Vakulin A, Hansen K, Zajamsek B, Wittert G, Catcheside P, Heinzer R, Eckert DJ. Sleep. 2022 Mar 4:zsac051. doi: 10.1093/sleep/zsac051.
Contact:Robert Adams

Testosterone, Diabetes Risk, and Diabetes Prevention in Men

Testosterone, Diabetes Risk, and Diabetes Prevention in Men. Yeap BB, Wittert GA. Endocrinol Metab Clin North Am. 2022 Mar;51(1):157-172. doi: 10.1016/j.ecl.2021.11.004. Epub 2022 Feb 8. PMID: 35216714.
Contact: Gary Wittert

Caring for someone with cancer in rural Australia

Caring for someone with cancer in rural Australia.

Gunn KM, Weeks M, Spronk KJJ, Fletcher C, Wilson C. Support Care Cancer. 2022 Feb 14. doi: 10.1007/s00520-022-06857-2.


Contact: Kate Gunn

The association between sleep microarchitecture and cognitive function in middle-aged and older men: a community-based cohort study

The association between sleep microarchitecture and cognitive function in middle-aged and older men: a community-based cohort study. Parker JL, Appleton SL, Melaku YA, D'Rozario AL, Wittert GA, Martin SA, Toson B, Catcheside PG, Lechat B, Teare AJ, Adams RJ, Vakulin A. J Clin Sleep Med. 2022 Feb 17. doi: 10.5664/jcsm.9934.

Contact: Jesse Parker

The science of preconception

McPherson NO, Grieger JA. The science of preconception. .International Journal of Birth and Parent Education. 2022;9(2):9-14.
Contact: Nicole Mcpherson

A review on Web-Based Interventions to Help Australian Adults Address Mental Well-being.

Web-Based Interventions to Help Australian Adults Address Depression, Anxiety, Suicidal Ideation, and General Mental Well-being: Scoping Review.

Skaczkowski G, van der Kruk S, Loxton S, Hughes-Barton D, Howell C, Turnbull D, Jensen N, Smout M, Gunn K. JMIR Ment Health. 2022 Feb 8;9(2):e31018. doi: 10.2196/31018. PMID: 35133281.

Contact: Kate Gunn

Measuring Reactive Oxygen Species in Semen for Male Preconception Care

Measuring Reactive Oxygen Species in Semen for Male Preconception Care: A Scientist Perspective.
Castleton, P.E.; Deluao, J.C.; Sharkey, D.J.; McPherson, N.O. Antioxidants 2022, 11, 264. https://doi.org/10.3390/antiox11020264
Contact: Nicole Mcpherson

DNA-PK has novel role in Metabolism by Regulating Glycolysis in Prostate Cancer

Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration Resistant Prostate Cancer.
Dylgjeri E, Kothari V, Shafi AA, Semenova G, Gallagher PT, Guan YF, Pang A, Goodwin JF, Irani S, McCann JJ, Mandigo AC, Chand S, McNair CM, Vasilevskaya I, Schiewer MJ, Lallas CD, McCue PA, Gomella LG, Seifert EL, Carroll JS, Butler LM, Holst J, Kelly WK, Knudsen KE.
Contact: Lisa Butler

Prostate cancer cell growth is influenced by cholesterol levels

Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover.
Raftopulos NL, Washaya TC, Niederprüm A, Egert A, Hakeem-Sanni MF, Varney B, Aishah A, Georgieva ML, Olsson E, Dos Santos DZ, Nassar ZD, Cochran BJ, Nagarajan SR, Kakani MS, Hastings JF, Croucher DR, Rye KA, Butler LM, Grewal T, Hoy AJ. Cancer Metab. 2022 Jan 15;10(1):1. doi: 10.1186/s40170-021-00278-1.PMID: 35033184
Contact: Lisa Butler

Farmers co-design of ifarmwell health and wellbeing platform

Combining Farmers' Preferences With Evidence-Based Strategies to Prevent and Lower Farmers' Distress: Co-design and Acceptability Testing of ifarmwell.
Gunn KM, Skaczkowski G, Dollman J, Vincent AD, Short CE, Brumby S, Barrett A, Harrison N, Turnbull D.JMIR Hum Factors. 2022 Jan 11;9(1):e27631. doi: 10.2196/27631.PMID: 35014963
Contact: Kate Gunn

Lingering effects of testosterone injections lead to long delay in recovery of male reproductive function

Recovery of Male Reproductive Function After Ceasing Prolonged Testosterone Undecanoate Injections
Handelsman DJ, Desai R, Conway AJ, Shankara-Narayana N, Stuckey BG, Inder WJ, Grossmann M, Yeap BB, Jesudason D, Ly LP, Bracken K, Wittert GA. Eur J Endocrinol. 2022 Jan 1:EJE-21-0608.R2. doi: 10.1530/EJE-21-0608. Online ahead of print.PMID: 35000898
Contact: Gary Wittert

Testosterone concentration associated with dementia in men: The UK Biobank prospective cohort study

Lower serum testosterone concentrations are associated with a higher incidence of dementia in men: The UK Biobank prospective cohort study.
Marriott RJ, Murray K, Flicker L, Hankey GJ, Matsumoto AM, Dwivedi G, Antonio L, Almeida OP, Bhasin S, Dobs AS, Handelsman DJ, Haring R, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Yeap BB. Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12529. Online ahead of print.PMID: 34978125
Contact: Gary Wittert

Relevance of testosterone & SHBG in cardiovascular disease in men

Associations of Serum Testosterone and Sex Hormone-Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men.
Yeap BB, Marriott RJ, Antonio L, Raj S, Dwivedi G, Reid CM, Anawalt BD, Bhasin S, Dobs AS, Handelsman DJ, Hankey GJ, Haring R, Matsumoto AM, Norman PE, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Ann Intern Med. 2021 Dec 28. doi: 10.7326/M21-0551. Online ahead of print.PMID: 34958606
Contact: Gary WIttert

Links between depression and lower urinary tract symptoms in men: screening implications

The bidirectional association between depression and lower urinary tract symptoms (LUTS) in men: A systematic review and meta-analysis of observational studies.
Martin SA, Tully PJ, Kahokehr AA, Jay A, Wittert GA. Neurourol Urodyn. 2022 Jan 12. doi: 10.1002/nau.24868. Online ahead of print.PMID: 35019156 Review.
Contact: Sean Martin

Abnormalities of sleep spindles, important for cognition, due to obstructive sleep apnoea

The association between obstructive sleep apnea and sleep spindles in middle-aged and older men: A community-based cohort study.
Parker JL, Melaku YA, D'Rozario AL, Wittert GA, Martin SA, Catcheside PG, Lechat B, Teare AJ, Adams RJ, Appleton SL, Vakulin A. Sleep. 2021 Nov 29:zsab282. doi: 10.1093/sleep/zsab282.PMID: 34850237.
Contact: Sarah Appleton

Fronteirs of Endocrinology Editorial: Couple Infertility

Editorial: The role of obesity and metabolic syndrome in couple infertility.
Marchiani S, Tamburrino L, McPherson N, Baldi E.. Front Endocrinol (Lausanne). 2021 Nov 10;12:784716. doi: 10.3389/fendo.2021.784716. PMID: 34858352.
Contact: Nicole McPherson

Safety & useability established for ExerciseGuide for men with metastatic prostate Ca

Acceptability and preliminary efficacy of a web- and telephone-based personalised exercise intervention for individuals with metastatic prostate cancer: The ExerciseGuide pilot randomised controlled trial. Cancers (Basel). 2021 Nov 25;13(23):5925. doi: 10.3390/cancers13235925. PMID: 34885036.
Evans HEL, Galvão DA, Forbes CC, Girard D, Vandelanotte C, Newton RU, Vincent AD, Wittert G, Kichenadasse G, Chambers S, Brook N, Short CE.
Contact: Holly Evans

Troubles-telling an important self-help tool for anxiety

“My skill is putting on a mask and convincing people not to look closer”: Silence, secrecy and self-reliance in men’s accounts of troubles-telling in an online discussion forum for anxiety.
Drioli-Phillips PG, Oxlad M, Scholz B, Lecouteur A, Feo R. The Journal of Men’s Studies. November 2021. doi:10.1177/10608265211052065
Contact: Phoebe Drioli-Phillips

Low circulating SHBG in men and increased risk of myocardial infarction

Associations of serum testosterone and sex hormone-binding globulin with incident cardiovascular events in middle-aged to older men.
Yeap BB, Marriott RJ, Antonio L, Raj S, Dwivedi G, Reid CM, Anawalt BD, Bhasin S, Dobs AS, Handelsman DJ, Hankey GJ, Haring R, Matsumoto AM, Norman PE, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Ann Intern Med. 2021 Dec 28. doi: 10.7326/M21-0551. Epub ahead of print. PMID: 34958606.
Contact: Gary.Wittert