Expendable young males.
Drummond M. Sport, Education and Society. 2021. DOI: 10.1080/13573322.2021.1992610
Contact: Murray Drummond
Expendable young males - expectations on young males in sports settings in Australia
Inhibition of ceramide metabolism combats enzalutamide resistance in prostate cancer
Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase.
Lin HM, Mak B, Yeung N, Huynh K, Meikle TG, Mellett NA, Kwan EM, Fettke H, Tran B, Davis ID, Mahon KL, Zhang A, Stockler MR, Briscoe K, Marx G, Crumbaker M, Stricker PD, Du P, Yu J, Jia S, Scheinberg T, Fitzpatrick M, Bonnitcha P, Sullivan DR, Joshua AM, Azad AA, Butler LM, Meikle PJ, Horvath LG.
EBioMedicine. 2021 Oct 14;72:103625. doi: 10.1016/j.ebiom.2021.103625. PMID: 34656931.
Contact: Lisa Butler
Blood triglycerides as a prompt to test for obstructive sleep apnoea in normal weight men
The association of obstructive sleep apnea and nocturnal hypoxemia with lipid profiles in a population-based study of community-dwelling Australian men.
Layla B Guscoth,1 Sarah L Appleton,2 Sean A Martin,1 Robert J Adams,2 Yohannes A Melaku,2 Gary A Wittert1 Nat Sci Sleep. 2021;13:1771-1782 https://doi.org/10.2147/NSS.S327478
Contact: Gary Wittert
World Alzheimers Day-meta-analysis published showing blood pressure variability increases risk of dementia
Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis.
de Heus RAA, Tzourio C, Lee EJL, Opozda M, Vincent AD, Anstey KJ, Hofman A, Kario K, Lattanzi S, Launer LJ, Ma Y, Mahajan R, Mooijaart SP, Nagai M, Peters R, Turnbull D, Yano Y; VARIABLE BRAIN Consortium, Claassen JAHR, Tully PJ.Hypertension. 2021 Sep 20:HYPERTENSIONAHA12117797. doi: 10.1161/HYPERTENSIONAHA.121.17797.
.PMID: 34538105
Contact: Phillip Tully
Live long and PROSPERO: A comment on Chiu and coworkers
Live long and PROSPERO: A comment on Chiu and coworkers.
Tully PJ, de Heus RAA; VARIABLE BRAIN Consortium.
J Clin Hypertens (Greenwich). 2021 Aug 29. doi: 10.1111/jch.14358. PMID: 34459092 Free article.
Contact: Phillip Tully
The role of the 6PGD protein in prostate cancer hormone treatment resistance
A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth.
Gillis JL, Hinneh JA, Ryan NK, Irani S, Moldovan M, Quek LE, Shrestha RK, Hanson AR, Xie J, Hoy AJ, Holst J, Centenera MM, Mills IG, Lynn DJ, Selth LA, Butler LM. Elife. 2021 Aug 12;10:e62592. doi: 10.7554/eLife.62592. PMID: 34382934.
Contact: Luke Selth
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.
Davies A, Nouruzi S, Ganguli D, Namekawa T, Thaper D, Linder S, Karaoğlanoğlu F, Omur ME, Kim S, Kobelev M, Kumar S, Sivak O, Bostock C, Bishop J, Hoogstraat M, Talal A, Stelloo S, van der Poel H, Bergman AM, Ahmed M, Fazli L, Huang H, Tilley W, Goodrich D, Feng FY, Gleave M, He HH, Hach F, Zwart W, Beltran H, Selth L, Zoubeidi A.
Nat Cell Biol. 2021 Sep;23(9):1023-1034. doi: 10.1038/s41556-021-00743-5. Epub 2021 Sep 6.PMID: 34489572
Contact: Luke Selth
Obesity, fatty acids and prostate cancer therapy resistance
Tumour fatty acid metabolism in the context of therapy resistance and obesity.
Hoy AJ, Nagarajan SR, Butler LM. Nat Rev Cancer. 2021 Aug 20. doi: 10.1038/s41568-021-00388-4. PMID: 34417571
Contact: Lisa Butler
Antioxidant idebenone for sperm of older men may be beneficial in improving embryo quality
Improving sperm oxidative stress and embryo quality in advanced paternal age using Idebenone in vitro-A proof-of-concept study. Nikitaras V, Zander-Fox D, McPherson NO. Antioxidants (Basel). 2021 Jul 5;10(7):1079. doi: 10.3390/antiox10071079. PMID: 34356315;
Contact: Nicole McPherson
Early chemotherapy for testicular cancer does extend time to relapse- UK study
Features and management of late relapse of nonseminomatous germ cell tumour. Jay APM, Aldiwani M, O'Callaghan ME, Pearce AK, Huddart RA, Mayer E, Reid AH, Nicol DL. Eur Urol Open Sci. 2021 Jun 7;29:82-88. doi: 10.1016/j.euros.2021.04.008. PMID: 34337537;
Contact: Michael O’Callaghan
PIEZO-ICSI increases fertilization rates compared with standard ICSI
PIEZO-ICSI increases fertilization rates compared with standard ICSI: a prospective cohort study. Zander-Fox D, Lam K, Pacella-Ince L, Tully C, Hamilton H, Hiraoka K, McPherson NO, Tremellen K. Reprod Biomed Online. 2021 May 31:S1472-6483(21)00279-0. doi: 10.1016/j.rbmo.2021.05.020. Epub ahead of print. PMID: 34326006.
Contact: Dr Nicole McPherson
World first study to catalog all lipid species in prostate cancer - informing future treatment strategies
Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition.
Butler LM, Mah CY, Machiels J, Vincent AD, Irani S, Mutuku SM, Spotbeen X, Bagadi M, Waltregny D, Moldovan M, Dehairs J, Vanderhoydonc F, Bloch K, Das R, Stahl J, Kench JG, Gevaert T, Derua R, Waelkens E, Nassar ZD, Selth LA, Trim PJ, Snel MF, Lynn DJ, Tilley WD, Horvath LG, Centenera MM, Swinnen JV.
Cancer Res. 2021 Aug 6:canres.3863.2020. doi: 10.1158/0008-5472.CAN-20-3863. PMID: 34362796
Contact: Lisa Butler
Optimisation of on-line exercise guide for men with metastatic prostate cancer
Usability, acceptability, and safety analysis of a computer-tailored web-based exercise intervention (ExerciseGuide) for individuals with metastatic prostate cancer: Multi-methods laboratory-based study..
Evans HE, Forbes CC, Galvão DA, Vandelanotte C, Newton RU, Wittert G, Chambers S, Vincent AD, Kichenadasse G, Girard D, Brook N, Short CE. JMIR Cancer. 2021 Jul 28;7(3):e28370. doi: 10.2196/28370. PMID: 34318759;
Contact: Holly Evans
Clinical review of inadequate nutrition and excessive energy expenditure on testosterone in men
Dysregulation of the Hypothalamic-Pituitary-Testicular Axis due to Energy Deficit.
Grossmann M, Wittert GA.J Clin Endocrinol Metab. 2021 Jul 15:dgab517. doi: 10.1210/clinem/dgab517. Online ahead of print.PMID: 34264314
Contact: Gary Wittert
Extending the Male Depression Risk Scale for use with older men
Extending the Male Depression Risk Scale for use with older men: the effect of age on factor structure and associations with psychological distress and history of depression.
Herreen D, Rice S, Ward L, Zajac I. Aging & Mental Health 2021. DOI: 10.1080/13607863.2021.1947966
Contact: Danielle Herreen