Aberrations in circulating ceramide levels are associated with poor clinical outcomes across localised and metastatic prostate cancer. Lin HM, Huynh K, Kohli M, Tan W, Azad AA, Yeung N, Mahon KL, Mak B, Sutherland PD, Shepherd A, Mellett N, Docanto M, Giles C, Centenera MM, Butler LM, Meikle PJ, Horvath LG.
Prostate Cancer Prostatic Dis. 2021 Mar 21. doi: 10.1038/s41391-021-00338-z.
Contact: Lisa Butler
Men with a high burden of depression symptoms are not receiving a diagnosis, despite regular GP visits
Effect of depression on health service utilisation in men: a prospective cohort study of Australian men aged 35 to 80 years. Martin S, Zajac I, Vincent A, Adams RJ, Appleton S, Wittert GA.
BMJ Open. 2021 Mar 17;11(3):e044893. doi: 10.1136/bmjopen-2020-044893
PMID: 33737438
Contact: Sean Martin
T4DM Sub-study finds testosterone increased volumetric cortical bone density in men>50 years
Effect of Testosterone treatment on bone microarchitecture and bone mineral density in men: a two-year RCT.Ng Tang Fui M, Hoermann R, Bracken K, Handelsman DJ, Inder WJ, Stuckey BGA, Yeap BB, Ghasem-Zadeh A, McLachlan R, Robledo KP, Jesudason D, Zajac JD, Wittert GA, Grossmann M.
.J Clin Endocrinol Metab. 2021 Mar 8:dgab149. doi: 10.1210/clinem/dgab149.
Contact: Gary Wittert
ELOVL5: Inching closer to a new therapeutic strategy for prostate cancer
ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer
Centenera MM, Scott JS, Machiels J, Nassar ZD, Miller DC, Zininos I, Dehairs J, Burvenich IJG, Zadra G, Chetta P, Bango C, Evergren E, Ryan NK, Gillis JL, Mah CY, Tieu T, Hanson AR, Carelli R, Bloch K, Panagopoulos V, Waelkens E, Derua R, Williams ED, Evdokioou A, Cifuentes-Rius A, Voelcker NH, Mills IG, Tilley WD, Scott AM, Loda M, Selth LA, Swinnen JV, Butler LM. Cancer Res. 2021 Feb 5:canres.2511.2020. doi: 10.1158/0008-5472.CAN-20-2511.
Contact: Maggie Centenera
Optimising tissues for laser-based lipid analysis during mass spectrometry
Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids
Truong JXM, Spotbeen X, White J, Swinnen JV, Butler LM, Snel MF, Trim PJ. Anal Bioanal Chem. 2021 Feb 9. doi: 10.1007/s00216-020-03128-z.
Contact: Jacob Truong
Psychological distress in drought-affected farmers
Why are some drought-affected farmers less distressed than others? The association between stress, psychological distress, acceptance, behavioral disengagement and neuroticism
Gunn KM, Turnbull DA, Dollman J, Kettler L, Bamford L, Vincent AD. Australian Journal of Rural Health. 2021 Feb 15. doi: 10.1111/ajr.12695.
Contact: Kate Gunn
Prostate cancer and exercise: Protocol for pilot study currently recruiting men
Evaluating a web- and telephone-based personalised exercise intervention for individuals living with metastatic prostate cancer (ExerciseGuide): protocol for a pilot randomised controlled trial
Evans HEL, Forbes CC, Galvão DA, Vandelanotte C, Newton RU, Wittert G, Chambers S, Vincent AD, Kichenadasse G, Brook N, Girard D, Short CE.
Pilot Feasibility Stud. 2021 Jan 11;7(1):21. doi: 10.1186/s40814-020-00763-2.
Contact: Camille Short
Culturing pancreatic tumour tissue provides novel ways to improve cancer knowledge
Ex vivo culture of intact human patient derived pancreatic tumour tissue.
Kokkinos J, Sharbeen G, Haghighi KS, Ignacio RMC, Kopecky C, Gonzales-Aloy E, Youkhana J, Timpson P, Pereira BA, Ritchie S, Pandzic E, Boyer C, Davis TP, Butler LM, Goldstein D, McCarroll JA, Phillips PA. Sci Rep. 2021 Jan 21;11(1):1944. doi: 10.1038/s41598-021-81299-0.
Contact: Lisa Butler
Achillea fragrantissima: The answer to better wound healing?
Ethanol Extract of Achillea fragrantissima Enhances Angiogenesis through Stimulation of VEGF Production
Hammad HM, Imraish A, Al-Hussaini M, Zihlif M, Harb AA, Abu Thiab TM, Lafi Z, Nassar ZD, Afifi FU. Endocr Metab Immune Disord Drug Targets. 2020 Dec 29. doi: 10.2174/1871530321666201230113018.
Contact: Zeyad Nassar
A pathway to address health inequities in young men and in men of colour
Reducing health inequities facing boys and young men of colour in the United States
Smith JA, Watkins DC, Griffit DM. Health Promot Int. 2020 Dec 27:daaa148. doi: 10.1093/heapro/daaa148.
Contact: James Smith
Analysis of helpline data highlight opportunities to improve services for men
A thematic analysis of men's help-seeking on an Australian health helpline
Lopriore S, Turnbull D, Martin SA. Health Promot J Austr. 2021 Jan 19. doi: 10.1002/hpja.458.
Contact: Sean Martin
Screening and referral is not enough: Cardiovascular disease and mental health
Screening and referral is not enough: a qualitative exploration of barriers to access and uptake of mental health services in patients with cardiovascular diseases
Collopy CM, Cosh SM, Tully PJ. BMC Health Serv Res. 2021 Jan 8;21(1):49. doi: 10.1186/s12913-020-06030-7.
Contact: Phil Tully
The androgen receptor: A promising treatment for breast cancer
The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer
Hickey TE, Selth LA, Chia KM, Laven-Law G, Milioli HH, Roden D, Jindal S, Hui M, Finlay-Schultz J, Ebrahimie E, Birrell SN, Stelloo S, Iggo R, Alexandrou S, Caldon CE, Abdel-Fatah TM, Ellis IO, Zwart W, Palmieri C, Sartorius CA, Swarbrick A, Lim E, Carroll JS, Tilley WD. Nat Med. 2021 Jan 18. doi: 10.1038/s41591-020-01168-7.
Contact: Wayne Tilley
Review: Fatty acid metabolism in cancer
The diversity and breadth of cancer cell fatty acid metabolism.
Nagarajan SR, Butler LM, Hoy AJ.
Cancer Metab. 2021 Jan 7;9(1):2. doi: 10.1186/s40170-020-00237-2. (Review)
Contact: Lisa Butler
miR-194: a potential therapeutic target to prevent drug resistant prostate cancer
Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer.
Fernandes RC, Toubia J, Townley S, Hanson AR, Dredge BK, Pillman KA, Bert AG, Winter JM, Iggo R, Das R, Obinata D; MURAL investigators, Sandhu S, Risbridger GP, Taylor RA, Lawrence MG, Butler LM, Zoubeidi A, Gregory PA, Tilley WD, Hickey TE, Goodall GJ, Selth LA. Cell Rep. 2021 Jan 5;34(1):108585. doi: 10.1016/j.celrep.2020.108585.
Contact: Luke Selth