Publications

Study extends evidence on circulating fats and clinical outcomes for men with prostate cancer

Study extends evidence on circulating fats and clinical outcomes for men with prostate cancer

Aberrations in circulating ceramide levels are associated with poor clinical outcomes across localised and metastatic prostate cancer. Lin HM, Huynh K, Kohli M, Tan W, Azad AA, Yeung N, Mahon KL, Mak B, Sutherland PD, Shepherd A, Mellett N, Docanto M, Giles C, Centenera MM, Butler LM, Meikle PJ, Horvath LG.
Prostate Cancer Prostatic Dis. 2021 Mar 21. doi: 10.1038/s41391-021-00338-z.
Contact: Lisa Butler

Men with a high burden of depression symptoms are not receiving a diagnosis, despite regular GP visits

Men with a high burden of depression symptoms are not receiving a diagnosis, despite regular GP visits

Effect of depression on health service utilisation in men: a prospective cohort study of Australian men aged 35 to 80 years. Martin S, Zajac I, Vincent A, Adams RJ, Appleton S, Wittert GA.
BMJ Open. 2021 Mar 17;11(3):e044893. doi: 10.1136/bmjopen-2020-044893
PMID: 33737438
Contact: Sean Martin

T4DM Sub-study finds testosterone increased volumetric cortical bone density in men>50 years

T4DM Sub-study finds testosterone increased volumetric cortical bone density in men>50 years

Effect of Testosterone treatment on bone microarchitecture and bone mineral density in men: a two-year RCT.Ng Tang Fui M, Hoermann R, Bracken K, Handelsman DJ, Inder WJ, Stuckey BGA, Yeap BB, Ghasem-Zadeh A, McLachlan R, Robledo KP, Jesudason D, Zajac JD, Wittert GA, Grossmann M.
.J Clin Endocrinol Metab. 2021 Mar 8:dgab149. doi: 10.1210/clinem/dgab149.
Contact: Gary Wittert

ELOVL5: Inching closer to a new therapeutic strategy for prostate cancer

ELOVL5: Inching closer to a new therapeutic strategy for prostate cancer

ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer
Centenera MM, Scott JS, Machiels J, Nassar ZD, Miller DC, Zininos I, Dehairs J, Burvenich IJG, Zadra G, Chetta P, Bango C, Evergren E, Ryan NK, Gillis JL, Mah CY, Tieu T, Hanson AR, Carelli R, Bloch K, Panagopoulos V, Waelkens E, Derua R, Williams ED, Evdokioou A, Cifuentes-Rius A, Voelcker NH, Mills IG, Tilley WD, Scott AM, Loda M, Selth LA, Swinnen JV, Butler LM. Cancer Res. 2021 Feb 5:canres.2511.2020. doi: 10.1158/0008-5472.CAN-20-2511.
Contact: Maggie Centenera

Psychological distress in drought-affected farmers

Psychological distress in drought-affected farmers

Why are some drought-affected farmers less distressed than others? The association between stress, psychological distress, acceptance, behavioral disengagement and neuroticism
Gunn KM, Turnbull DA, Dollman J, Kettler L, Bamford L, Vincent AD. Australian Journal of Rural Health. 2021 Feb 15. doi: 10.1111/ajr.12695.
Contact: Kate Gunn

Prostate cancer and exercise: Protocol for pilot study currently recruiting men

Prostate cancer and exercise: Protocol for pilot study currently recruiting men

Evaluating a web- and telephone-based personalised exercise intervention for individuals living with metastatic prostate cancer (ExerciseGuide): protocol for a pilot randomised controlled trial
Evans HEL, Forbes CC, Galvão DA, Vandelanotte C, Newton RU, Wittert G, Chambers S, Vincent AD, Kichenadasse G, Brook N, Girard D, Short CE.
Pilot Feasibility Stud. 2021 Jan 11;7(1):21. doi: 10.1186/s40814-020-00763-2.
Contact: Camille Short

Culturing pancreatic tumour tissue provides novel ways to improve cancer knowledge

Culturing pancreatic tumour tissue provides novel ways to improve cancer knowledge

Ex vivo culture of intact human patient derived pancreatic tumour tissue.
Kokkinos J, Sharbeen G, Haghighi KS, Ignacio RMC, Kopecky C, Gonzales-Aloy E, Youkhana J, Timpson P, Pereira BA, Ritchie S, Pandzic E, Boyer C, Davis TP, Butler LM, Goldstein D, McCarroll JA, Phillips PA. Sci Rep. 2021 Jan 21;11(1):1944. doi: 10.1038/s41598-021-81299-0.
Contact: Lisa Butler

Achillea fragrantissima: The answer to better wound healing?

Achillea fragrantissima: The answer to better wound healing?

Ethanol Extract of Achillea fragrantissima Enhances Angiogenesis through Stimulation of VEGF Production
Hammad HM, Imraish A, Al-Hussaini M, Zihlif M, Harb AA, Abu Thiab TM, Lafi Z, Nassar ZD, Afifi FU. Endocr Metab Immune Disord Drug Targets. 2020 Dec 29. doi: 10.2174/1871530321666201230113018.
Contact: Zeyad Nassar

Screening and referral is not enough: Cardiovascular disease and mental health

Screening and referral is not enough: Cardiovascular disease and mental health

The androgen receptor: A promising treatment for breast cancer

The androgen receptor: A promising treatment for breast cancer

The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer
Hickey TE, Selth LA, Chia KM, Laven-Law G, Milioli HH, Roden D, Jindal S, Hui M, Finlay-Schultz J, Ebrahimie E, Birrell SN, Stelloo S, Iggo R, Alexandrou S, Caldon CE, Abdel-Fatah TM, Ellis IO, Zwart W, Palmieri C, Sartorius CA, Swarbrick A, Lim E, Carroll JS, Tilley WD. Nat Med. 2021 Jan 18. doi: 10.1038/s41591-020-01168-7.
Contact: Wayne Tilley

miR-194: a potential therapeutic target to prevent drug resistant prostate cancer

miR-194: a potential therapeutic target to prevent drug resistant prostate cancer

Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer.
Fernandes RC, Toubia J, Townley S, Hanson AR, Dredge BK, Pillman KA, Bert AG, Winter JM, Iggo R, Das R, Obinata D; MURAL investigators, Sandhu S, Risbridger GP, Taylor RA, Lawrence MG, Butler LM, Zoubeidi A, Gregory PA, Tilley WD, Hickey TE, Goodall GJ, Selth LA. Cell Rep. 2021 Jan 5;34(1):108585. doi: 10.1016/j.celrep.2020.108585.
Contact: Luke Selth